Daily Papers

Accurate delineation of anatomical structures in volumetric CT scans is crucial for diagnosis and treatment planning. While AI has advanced automated segmentation, current approaches typically target individual structures, creating a fragmented landscape of incompatible models with varying performance and disparate evaluation protocols. Foundational segmentation models address these limitations by providing a holistic anatomical view through a single model. Yet, robust clinical deployment demands comprehensive training data, which is lacking in existing whole-body approaches, both in terms of data heterogeneity and, more importantly, anatomical coverage. In this work, rather than pursuing incremental optimizations in model architecture, we present CADS, an open-source framework that prioritizes the systematic integration, standardization, and labeling of heterogeneous data sources for whole-body CT segmentation. At its core is a large-scale dataset of 22,022 CT volumes with complete annotations for 167 anatomical structures, representing a significant advancement in both scale and coverage, with 18 times more scans than existing collections and 60% more distinct anatomical targets. Building on this diverse dataset, we develop the CADS-model using established architectures for accessible and automated full-body CT segmentation. Through comprehensive evaluation across 18 public datasets and an independent real-world hospital cohort, we demonstrate advantages over SoTA approaches. Notably, thorough testing of the model's performance in segmentation tasks from radiation oncology validates its direct utility for clinical interventions. By making our large-scale dataset, our segmentation models, and our clinical software tool publicly available, we aim to advance robust AI solutions in radiology and make comprehensive anatomical analysis accessible to clinicians and researchers alike.

While conditional diffusion models are known to have good coverage of the data distribution, they still face limitations in output diversity, particularly when sampled with a high classifier-free guidance scale for optimal image quality or when trained on small datasets. We attribute this problem to the role of the conditioning signal in inference and offer an improved sampling strategy for diffusion models that can increase generation diversity, especially at high guidance scales, with minimal loss of sample quality. Our sampling strategy anneals the conditioning signal by adding scheduled, monotonically decreasing Gaussian noise to the conditioning vector during inference to balance diversity and condition alignment. Our Condition-Annealed Diffusion Sampler (CADS) can be used with any pretrained model and sampling algorithm, and we show that it boosts the diversity of diffusion models in various conditional generation tasks. Further, using an existing pretrained diffusion model, CADS achieves a new state-of-the-art FID of 1.70 and 2.31 for class-conditional ImageNet generation at 256times256 and 512times512 respectively.

NLP models are used in a variety of critical social computing tasks, such as detecting sexist, racist, or otherwise hateful content. Therefore, it is imperative that these models are robust to spurious features. Past work has attempted to tackle such spurious features using training data augmentation, including Counterfactually Augmented Data (CADs). CADs introduce minimal changes to existing training data points and flip their labels; training on them may reduce model dependency on spurious features. However, manually generating CADs can be time-consuming and expensive. Hence in this work, we assess if this task can be automated using generative NLP models. We automatically generate CADs using Polyjuice, ChatGPT, and Flan-T5, and evaluate their usefulness in improving model robustness compared to manually-generated CADs. By testing both model performance on multiple out-of-domain test sets and individual data point efficacy, our results show that while manual CADs are still the most effective, CADs generated by ChatGPT come a close second. One key reason for the lower performance of automated methods is that the changes they introduce are often insufficient to flip the original label.

Open-Vocabulary Object Detection (OVOD) aims to detect novel objects beyond a given set of base categories on which the detection model is trained. Recent OVOD methods focus on adapting the image-level pre-trained vision-language models (VLMs), such as CLIP, to a region-level object detection task via, eg., region-level knowledge distillation, regional prompt learning, or region-text pre-training, to expand the detection vocabulary. These methods have demonstrated remarkable performance in recognizing regional visual concepts, but they are weak in exploiting the VLMs' powerful global scene understanding ability learned from the billion-scale image-level text descriptions. This limits their capability in detecting hard objects of small, blurred, or occluded appearance from novel/base categories, whose detection heavily relies on contextual information. To address this, we propose a novel approach, namely Simple Image-level Classification for Context-Aware Detection Scoring (SIC-CADS), to leverage the superior global knowledge yielded from CLIP for complementing the current OVOD models from a global perspective. The core of SIC-CADS is a multi-modal multi-label recognition (MLR) module that learns the object co-occurrence-based contextual information from CLIP to recognize all possible object categories in the scene. These image-level MLR scores can then be utilized to refine the instance-level detection scores of the current OVOD models in detecting those hard objects. This is verified by extensive empirical results on two popular benchmarks, OV-LVIS and OV-COCO, which show that SIC-CADS achieves significant and consistent improvement when combined with different types of OVOD models. Further, SIC-CADS also improves the cross-dataset generalization ability on Objects365 and OpenImages. The code is available at https://github.com/mala-lab/SIC-CADS.