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Captopril, sold under the brand name Capoten among others, is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of congestive heart failure. Captopril was the first oral ACE inhibitor found for the treatment of hypertension. It does not cause fatigue as associated wi...
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Enantiopure drugs
Levetiracetam, sold under the brand name Keppra among others, is a medication used to treat epilepsy. It is used for partial-onset, myoclonic, or tonic–clonic seizures and is taken either by mouth as an immediate or extended release formulation or by injection into a vein. Common side effects of levetiracetam include s...
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Enantiopure drugs
Adverse effects are typically mild to moderate. However, severe, disabling, and potentially irreversible adverse effects sometimes occur, and for this reason it is recommended that use of fluoroquinolones be limited. Prominent among these are adverse effects that became the subject of a black box warning by the FDA in ...
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Enantiopure drugs
The volume of distribution of levetiracetam is similar to total body water. Levetiracetam modestly binds to plasma proteins (less than 10%).
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Enantiopure drugs
In 1978 the United States banned the use of CFCs such as Freon in aerosol cans, the beginning of a long series of regulatory actions against their use. The critical DuPont manufacturing patent for Freon ("Process for Fluorinating Halohydrocarbons", U.S. Patent #3258500) was set to expire in 1979. In conjunction with ot...
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Greenhouse Gases
Exemestane is quickly absorbed from the gut, but undergoes a strong first-pass effect in the liver. Highest blood plasma concentrations are reached after 1.2 hours in breast cancer patients and after 2.9 hours in healthy subjects. Maximal aromatase inhibition occurs after two to three days. 90% of the absorbed substanc...
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Enantiopure drugs
CO absorbs the ground's thermal radiation mainly at wavelengths between 13 and 17 micron. At this wavelength range, it is almost solely responsible for the attenuation of radiation from the ground. The amount of ground radiation that is transmitted through the atmosphere in each wavelength is related to the optical dep...
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Greenhouse Gases
Since 1 January 2010, it has been illegal to use newly manufactured HCFCs to service refrigeration and air-conditioning equipment; only reclaimed and recycled HCFCs may be used. In practice this means that the gas has to be removed from the equipment before servicing and replaced afterwards, rather than refilling with...
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Greenhouse Gases
ICOS consists of a network of standardized, long-term, high-precision integrated monitoring of atmospheric greenhouse gas concentrations and fluxes. The infrastructure integrates terrestrial and atmospheric observations at various sites into a single, coherent, highly precise dataset. This data allows a unique regional...
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Greenhouse Gases
Lisinopril is typically used for the treatment of high blood pressure, congestive heart failure, and diabetic nephropathy and after acute myocardial infarction (heart attack). Lisinopril is part of the ACE inhibitors drug class. Lisinopril is indicated for the treatment of hypertension, adjunctive therapy for heart fai...
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Enantiopure drugs
In 2018, the atmospheric concentration of CFC-11 was noted by researchers to be declining more slowly than expected, and it subsequently emerged that it remains in widespread use as a blowing agent for polyurethane foam insulation in the construction industry of China. In 2021, researchers announced that emissions dec...
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Greenhouse Gases
Flutamide is marketed widely throughout the world, including in the United States, Canada, Europe, Australia, New Zealand, South Africa, Central and South America, East and Southeast Asia, India, and the Middle East.
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Enantiopure drugs
The concentration of HCFC-142b in the atmosphere grew to over 20 parts per trillion by year 2010. It has an ozone depletion potential (ODP) of 0.07. This is low compared to the ODP=1 of trichlorofluoromethane (CFC-11, R-11), which also grew about ten times more abundant in the atmosphere by year 1985 (prior to intro...
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Greenhouse Gases
Lisinopril is the lysine-analog of enalapril. Unlike other ACE inhibitors, it is not a prodrug, is not metabolized by the liver, and is excreted unchanged in the urine.
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Enantiopure drugs
Oxacillin (trade name Bactocill) is a narrow-spectrum beta-lactam antibiotic of the penicillin class developed by Beecham. It was patented in 1960 and approved for medical use in 1962.
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During application, the building is enclosed and filled with the gas for a period of time, usually at least 16–18 hours, sometimes as long as 72 hours. The building must then be ventilated, generally for at least 6 hours, before occupants can return. California regulations are such that the tent will be on for three t...
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Greenhouse Gases
Escitalopram appears to be effective in treating generalized anxiety disorder, with relapse on escitalopram at 20% rather than placebo at 50%, which translates to a number needed to treat of 3.33. Escitalopram appears effective in treating social anxiety disorder as well.
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Flutamide has been used in case reports to decrease the frequency of spontaneous orgasms, for instance in men with post-orgasmic illness syndrome.
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Cefalexin, also spelled cephalexin, is an antibiotic that can treat a number of bacterial infections. It kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cefalexin is a β-lactam antibiotic within the class of first-generation cephalosporins. It works similarly to ...
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Enantiopure drugs
Dexmedetomidine may enhance the effects of other sedatives and anesthetics when co-administered. Similarly, drugs that lower blood pressure and heart rate, such as beta blockers, may also have enhanced effects when co-administered with dexmedetomidine.
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Enantiopure drugs
Its membership in the amphetamine class has made pseudoephedrine a sought-after chemical precursor in the illicit manufacture of methamphetamine and methcathinone. As a result of the increasing regulatory restrictions on the sale and distribution of pseudoephedrine, pharmaceutical firms have reformulated medications to...
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Enantiopure drugs
CFC-13like all chlorofluorocarbon compoundscontains atoms of carbon (C), chlorine (Cl), and fluorine (F). It can be prepared by reacting carbon tetrachloride with hydrogen fluoride in the presence of a catalytic amount of antimony pentachloride: CCl + 3HF CClF + 3HCl This reaction can also produce trichlorofluorometh...
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Greenhouse Gases
Flutamide, sold under the brand name Eulexin among others, is a nonsteroidal antiandrogen (NSAA) which is used primarily to treat prostate cancer. It is also used in the treatment of androgen-dependent conditions like acne, excessive hair growth, and high androgen levels in women. It is taken by mouth, usually three ti...
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The development of Hydrofluoroolefins (HFOs) as replacements for Hydrochlorofluorocarbons and Hydrofluorocarbons began after the Kigali amendment to the Montreal Protocol in 2016, which called for the phase out of high global warming potential (GWP) refrigerants and to replace them with other refrigerants with a lower ...
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Greenhouse Gases
Dextroamphetamine is also used recreationally as a euphoriant and aphrodisiac, and like other amphetamines is used as a club drug for its energetic and euphoric high. Dextroamphetamine is considered to have a high potential for misuse in a recreational manner since individuals typically report feeling euphoric, more al...
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A number of technologies remove greenhouse gases emissions from the atmosphere. Most widely analyzed are those that remove carbon dioxide from the atmosphere, either to geologic formations such as bio-energy with carbon capture and storage and carbon dioxide air capture, or to the soil as in the case with biochar. Many...
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Greenhouse Gases
The mechanism of action of armodafinil is unknown. Armodafinil (R-(−)-modafinil) has pharmacological properties almost identical to those of modafinil (a mixture of R-(−)- and (S)-(+)-modafinil). The (R)- and (S)-enantiomers have similar pharmacological action in animals. Armodafinil has wake-promoting actions similar ...
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Enantiopure drugs
Dexmedetomidine, sold under the trade name Precedex among others, is a drug used in humans for sedation. Veterinarians use dexmedetomidine for similar purposes in treating cats, dogs, and horses. It is also used in humans to treat acute agitation associated with schizophrenia or bipolar I or II disorder. Similar to clo...
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Enantiopure drugs
Several routes exist for the synthesis of Dextromethorphan. Even though many of the syntheses have been known since the middle of the 20th century, researchers are still working today to further develop the synthesis of Dextromethorphan and, for example, to make it more environmentally friendly. This includes the synth...
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In the United States, the regulation of F-gases falls under the authority of the Environmental Protection Agency's overall attempts to combat greenhouse gases. The United States has put forward a joint proposal with Mexico and the Federated States of Micronesia for a phase-down of HFCs by 2030. The American Innovation ...
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Greenhouse Gases
Novec 649 is a low-temperature heat-transfer fluid. It has been used as a full-immersion fluid in a proof of concept data center cooling system by Intel and SGI. As it boils off easily due to its boiling point, it is used in two-phase immersion cooling system with a condensing loop running cold water. Effects of evapo...
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Greenhouse Gases
is a potent greenhouse gas. A ton of HFC-23 in the atmosphere has the same effect as 11,700 tons of carbon dioxide. This equivalency, also called a 100-yr global warming potential, is slightly larger at 14,800 for HFC-23. The atmospheric lifetime is 270 years. HFC-23 was the most abundant HFC in the global atmosphere u...
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Greenhouse Gases
Fluoroalkenes polymerize more exothermically than normal alkenes. Unsaturated fluorocarbons have a driving force towards sp hybridization due to the electronegative fluorine atoms seeking a greater share of bonding electrons with reduced s character in orbitals. The most famous member of this class is tetrafluoroethyle...
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Greenhouse Gases
In 2010, CDP was called "The most powerful green NGO you've never heard of" by the Harvard Business Review. In 2012 it won the Zayed Future Energy Prize.
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Greenhouse Gases
Water is the chemical substance with chemical formula ; one molecule of water has two hydrogen atoms covalently bonded to a single oxygen atom. Water is a tasteless, odorless liquid at ambient temperature and pressure. Liquid water has weak absorption bands at wavelengths of around 750 nm which cause it to appear to ha...
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Greenhouse Gases
Dexmedetomidine may be useful for the treatment of the negative cardiovascular effects of acute amphetamines and cocaine intoxication and overdose. Dexmedetomidine has also been used as an adjunct to neuroaxial anesthesia for lower limb procedures. It has been successfully used to treat opioid withdrawal symptoms. In 2...
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Enantiopure drugs
R-22 was mostly phased out in new equipment in the United States by regulatory action by the EPA under the Significant New Alternatives Program (SNAP) by rules 20 and 21 of the program, due to its high global warming potential. The EPA program was consistent with the Montreal Accords, but international agreements must ...
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Greenhouse Gases
The racemic parent compound racemorphan was first described in a Swiss and US patent application from Hoffmann-La Roche in 1946 and 1947, respectively; a patent was granted in 1950. A resolution of the two isomers of racemorphan with tartaric acid was published in 1952, and dextromethorphan was successfully tested in 1...
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Earth absorbs some of the radiant energy received from the sun, reflects some of it as light and reflects or radiates the rest back to space as heat. A planets surface temperature depends on this balance between incoming and outgoing energy. When Earths energy balance is shifted, its surface becomes warmer or cooler, l...
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Greenhouse Gases
In sedimentary layers throughout the Arctic basin, a unit reaching at least 8 m in thickness (the bottom of the longest core was not recovered, but it may have reached 20 m+) is discernible. This unit consists of alternating layers; siliceous clastic layers representing the background sedimentation of planktonic organ...
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Greenhouse Gases
LAAM was approved in 1993 by the U.S. Food and Drug Administration for use in the treatment of opioid dependence. In 2001, LAAM was removed from the European market due to reports of life-threatening ventricular rhythm disorders. In 2003, Roxane Laboratories, Inc. discontinued Orlaam in the US.
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Gestonorone caproate is used in the palliative treatment of benign prostatic hypertrophy and endometrial cancer. It is used at a dose of 100 to 200 mg once a week by intramuscular injection.
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Lisinopril does not bind to proteins in the blood. It does not distribute as well in people with NYHA Class II–IV heart failure.
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Unlike alkyl halide refrigerants that contain bromine or chlorine, R-410A (which contains only fluorine) does not contribute to ozone depletion and is therefore becoming more widely used as ozone-depleting refrigerants like R-22 are phased out. However, like methane, its global warming potential (GWP) is appreciably wo...
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Greenhouse Gases
It once was a popular solvent in organic chemistry, but because of its adverse health effects, it is rarely used today. It is sometimes useful as a solvent for infrared spectroscopy, because there are no significant absorption bands above 1600 cm. Because carbon tetrachloride does not have any hydrogen atoms, it was hi...
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Greenhouse Gases
Benazepril, sold under the brand name Lotensin among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. It is a reasonable initial treatment for high blood pressure. It is taken by mouth. Versions are available as the combinations benazepril/hydrochlorothiazide and be...
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Enantiopure drugs
"Amoxicillin" is the International Nonproprietary Name (INN), British Approved Name (BAN), and United States Adopted Name (USAN), while "amoxycillin" is the Australian Approved Name (AAN). Amoxicillin is one of the semisynthetic penicillins discovered by former pharmaceutical company Beecham Group. The patent for amoxi...
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Enantiopure drugs
In persons with normal kidney function, levetiracetam is eliminated from the body primarily by the kidneys with about 66 percent of the original drug passed unchanged into urine. The plasma half-life of levetiracetam in adults is about 6 to 8 hours although the mean CSF half life of approx. 24 hours better reflects le...
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Enantiopure drugs
Levofloxacin is used to treat infections including: respiratory tract infections, cellulitis, urinary tract infections, prostatitis, anthrax, endocarditis, meningitis, pelvic inflammatory disease, traveler's diarrhea, tuberculosis, and plague and is available by mouth, intravenously, and in eye drop form. As of 2016, t...
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The average wholesale price (AWP) for oxacillin products are provided as follows. The prices listed below are intended to serve as reference values and do not represent the pricing determined by any single manufacturer or entity. *Bactocill in Dextrose Intravenous **1 g/50 mL: $20.37 **2 g/50 mL: $32.48 *Oxacillin Sod...
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Enantiopure drugs
Since the time history of CFC concentrations in the atmosphere is relatively well known, they have provided an important constraint on ocean circulation. CFCs dissolve in seawater at the ocean surface and are subsequently transported into the ocean interior. Because CFCs are inert, their concentration in the ocean inte...
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Greenhouse Gases
Amoxicillin is also sometimes used as an antibiotic for animals. The use of amoxicillin for animals intended for human consumption (chickens, cattle, and swine for example) has been approved.
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Studies suggest dexmedetomidine for sedation in mechanically ventilated adults may reduce time to extubation and ICU stay. Compared with other sedatives, some studies suggest dexmedetomidine may be associated with less delirium. However, this finding is not consistent across multiple studies. At the very least, when ag...
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Enantiopure drugs
The molecule is tetrahedral with C symmetry. The S-O distance is 140.5 pm, S-F is 153.0 pm. As predicted by VSEPR, the O-S-O angle is more open than the F-S-F angle, 124° and 97°, respectively. One synthesis begins with the preparation of potassium fluorosulfite: :SO + KF → KSOF This salt is then chlorinated to gi...
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Greenhouse Gases
Duke University did a study where they dosed a loblolly pine plantation with elevated levels of . The studies showed that the pines did indeed grow faster and stronger. They were also less prone to damage during ice storms, which is a factor that limits loblolly growth farther north. The forest did relatively better du...
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Greenhouse Gases
The FDA estimated that in 2011, over 23 million outpatient prescriptions for fluoroquinolones, of which levofloxacin made up 28%, were filled in the United States.
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Enantiopure drugs
In Earth's atmosphere, carbon dioxide is a trace gas that plays an integral part in the greenhouse effect, carbon cycle, photosynthesis and oceanic carbon cycle. It is one of several greenhouse gases in the atmosphere of Earth. The current global average concentration of carbon dioxide (CO) in the atmosphere is 421 ppm...
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Greenhouse Gases
CDPs climate change program aims to reduce companies greenhouse gas emissions and mitigate climate change risk. CDP requests information on climate risks and low carbon opportunities from the world's largest companies on behalf of over 800 institutional investor signatories with a combined US$100 trillion in assets.
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Greenhouse Gases
Fluorocarbons are chemical compounds with carbon-fluorine bonds. Compounds that contain many C-F bonds often have distinctive properties, e.g., enhanced stability, volatility, and hydrophobicity. Several fluorocarbons and their derivatives are commercial polymers, refrigerants, drugs, and anesthetics.
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Greenhouse Gases
Perfluorocarbons dissolve relatively high volumes of gases. The high solubility of gases is attributed to the weak intermolecular interactions in these fluorocarbon fluids. The table shows values for the mole fraction, , of nitrogen dissolved, calculated from the Blood–gas partition coefficient, at 298.15 K (25 °C), 0....
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Greenhouse Gases
Water vapor is a by-product of respiration in plants and animals. Its contribution to the pressure, increases as its concentration increases. Its partial pressure contribution to air pressure increases, lowering the partial pressure contribution of the other atmospheric gases (Dalton's Law). The total air pressure must...
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Greenhouse Gases
In placebo-controlled studies, the most commonly observed side effects were headache, xerostomia (dry mouth), nausea, dizziness, and insomnia. Possible side effects also include depression, anxiety, hallucinations, euphoria, extreme increase in activity and talking, anorexia, tremor, thirst, rash, suicidal thoughts, an...
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Enantiopure drugs
Medical uses include: * High blood pressure * Congestive heart failure * Following heart attack in people with evidence of heart failure * People over 55 years at high risk: prevention of heart attack, stroke, cardiovascular death, or in need of revascularization procedures * Prevent the onset and/or delay the progress...
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Amoxicillin is effective for treatment of early cutaneous Lyme borreliosis; the effectiveness and safety of oral amoxicillin is neither better nor worse than common alternatively-used antibiotics.
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Single doses of up to at least 32-fold (800 mg), as well as continuous therapy with 24-fold (600 mg) the usual daily dose are well tolerated. No life-threatening overdosing is known in humans, but only in animal studies with 2000- to 4000-fold doses (adjusted to body surface area).
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Piperacillin is generally available in their stable form as crystallized potassium or sodium salt, quickly losing bactericidal activity upon dissolution due to their short half-lives. As the gastrointestinal tract does not absorb piperacillin and tazobactam, they are dissolved in a solution before being administered to...
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Enantiopure drugs
Cefuroxime, sold under the brand name Zinacef among others, is a second-generation cephalosporin antibiotic used to treat and prevent a number of bacterial infections. These include pneumonia, meningitis, otitis media, sepsis, urinary tract infections, and Lyme disease. It is used by mouth or by injection into a vein o...
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CDP recognizes companies with high-quality disclosure in its annual scoring process, with top companies making it onto CDP's so-called A-list. Scores are calculated according to a standardized method which measures whether and how well a company responds to each question. A company goes through four main steps, startin...
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Greenhouse Gases
Fluoroalkenes and fluorinated alkynes are reactive and many are toxic for example perfluoroisobutene. To produce polytetrafluoroethylene various fluorinated surfactants are used, in the process known as Emulsion polymerization, and the surfactant included in the polymer can bioaccumulate.
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Greenhouse Gases
Phenoxymethylpenicillin, also known as penicillin V (PcV) and penicillin VK, is an antibiotic useful for the treatment of a number of bacterial infections. Specifically it is used for the treatment of strep throat, otitis media, and cellulitis. It is also used to prevent rheumatic fever and to prevent infections follow...
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Haloalkanes are diverse in their properties, making generalizations difficult. Few are acutely toxic, but many pose risks from prolonged exposure. Some problematic aspects include carcinogenicity and liver damage (e.g., carbon tetrachloride). Under certain combustion conditions, chloromethanes convert to phosgene, whic...
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Greenhouse Gases
Levorphanol (brand name Levo-Dromoran) is an opioid medication used to treat moderate to severe pain. It is the levorotatory enantiomer of the compound racemorphan. Its dextrorotatory counterpart is dextrorphan. It was first described in Germany in 1946. The drug has been in medical use in the United States since 1953.
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In its pill form, selegiline is used to treat symptoms of Parkinson's disease. It is most often used as an adjunct to drugs such as levodopa (-DOPA), although it has been used off-label as a monotherapy. The rationale for adding selegiline to levodopa is to decrease the required dose of levodopa and thus reduce the mot...
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Enantiopure drugs
While a verdant Arctic Ocean is a viable working model, skeptical scientists point out that it would be possible for Azolla colonies in river deltas or freshwater lagoons to be swept into the Arctic Ocean by strong currents, removing the necessity for a freshwater layer.
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Greenhouse Gases
Dexmedetomidine, under the trade name Dexdomitor (Orion Corporation), was approved in the European Union in for use in cats and dogs in 2002, for sedation and induction of general anesthesia. The FDA approved dexmedetomidine for use in dogs in 2006 and cats in 2007. In 2015, the European Medicines Agency and the FDA ap...
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Enantiopure drugs
According to Plumb's Veterinary Medication Guides, cefalexin can be used in treating skin, respiratory tract, and urinary tract infections. Specifically, it can be used to treat pyoderma in dogs. The U.S. Food and Drug Administration (FDA) has approved it for use in humans and dogs but not for other species. Like other...
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Enantiopure drugs
Enalapril has an L-proline moiety as a part of the molecule which is responsible for the oral bioavailability of the drug. It is a pro-drug, which means that it exerts its function after being metabolized. The "-OCH2CH3" part of the molecule will split during the metabolism and at the carbon will be a carboxylate, whic...
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Enantiopure drugs
Sedative hypnotic drugs including eszopiclone are more commonly prescribed to the elderly than to younger patients despite benefits of medication being generally unimpressive. In 2015, the American Geriatrics Society reviewed the safety information about eszopiclone and similar drugs and concluded that the "nonbenzodia...
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Enantiopure drugs
As of November 2019, arketamine is under development for the treatment of depression under the developmental code names PCN-101 by Perception Neuroscience in the United States and HR-071603 by Jiangsu Hengrui Medicine in China.
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These have been no reports of serious adverse effects with overdose of drospirenone. Symptoms that may occur in the event of an overdose may include nausea, vomiting, and vaginal bleeding. There is no antidote for overdose of drospirenone and treatment of overdose should be based on symptoms. Since drospirenone has ant...
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Enantiopure drugs
The use of oxacillin is contraindicated in individuals that have experienced a hypersensitivity reaction to any medication in the penicillin family of antibiotics. Cross-allergenicity has been documented in individuals taking oxacillin that experienced a previous hypersensitivity reaction when given cephalosporins and ...
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Enantiopure drugs
Amoxicillin is used in the treatment of a number of infections, including acute otitis media, streptococcal pharyngitis, pneumonia, skin infections, urinary tract infections, Salmonella infections, Lyme disease, and chlamydia infections.
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Enantiopure drugs
The principal components of volcanic gases are water vapor (HO), carbon dioxide (CO), sulfur either as sulfur dioxide (SO) (high-temperature volcanic gases) or hydrogen sulfide (HS) (low-temperature volcanic gases), nitrogen, argon, helium, neon, methane, carbon monoxide and hydrogen. Other compounds detected in volcan...
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Greenhouse Gases
The OCO-2 satellite was built by Orbital Sciences Corporation, based around the LEOStar-2 bus. The spacecraft is being used to study carbon dioxide concentrations and distributions in the atmosphere. OCO-2 was ordered after the original OCO spacecraft failed to achieve orbit. During the first satellite's launch atop a ...
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Greenhouse Gases
Illicit diversion of pseudoephedrine in Australia has caused significant changes to the way the products are regulated. , all products containing pseudoephedrine have been rescheduled as either "Pharmacist Only Medicines" (Schedule 3) or "Prescription Only Medicines" (Schedule 4), depending on the amount of pseudoephed...
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Enantiopure drugs
EPA's analysis indicated the amount of existing inventory was between 22,700t and 45,400t. In 2012 the EPA reduced the amount of R-22 by 45%, causing the price to rise by more than 300%. For 2013, the EPA has reduced the amount of R-22 by 29%.
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Greenhouse Gases
Some people experience persistent sexual side effects when taking SSRIs or after discontinuing them. Symptoms of medication-induced sexual dysfunction from antidepressants include difficulty with orgasm, erection, or ejaculation. Other symptoms may be genital anesthesia, anhedonia, decreased libido, vaginal lubrication...
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Armodafinil is readily absorbed after oral administration. The absolute oral bioavailability was not determined due to the aqueous insolubility of armodafinil, which precluded intravenous administration. Peak plasma concentrations are attained at approximately 2 hours in the fasted state. Food effect on the overall bio...
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Kidney impairment decreases the rate of elimination of levetiracetam from the body. Individuals with reduced kidney function may require dose adjustments. Kidney function can be estimated from the rate of creatinine clearance. Dose adjustment of levetiracetam is not necessary in liver impairment.
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Levonorgestrel can be taken by mouth as a form of emergency birth control. The typical dosage is either 1.5 mg taken once or 0.75 mg taken 12–24 hours apart. The effectiveness in both methods is similar. The most widely used form of oral emergency contraception is the progestin-only pill, which contains a 1.5 mg dosage...
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It is a gaseous mixture of 60-80% tetrafluoroethane (R-134a), 10-30% pentafluoroethane (R-125) and 10-30% carbon dioxide (CO). Its physical properties are similar to those of Halon 1301.
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Greenhouse Gases
Mecillinam is used in the treatment of infections due to susceptible gram-negative bacteria, especially urinary tract infections which are most commonly caused by Escherichia coli. Mecillinam is active against most pathogenic Gram-negative bacteria, except Pseudomonas aeruginosa and some species of Proteus. Several stu...
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Enantiopure drugs
Pseudoephedrine is a stimulant, but it is well known for shrinking swollen nasal mucous membranes, so it is often used as a decongestant. It reduces tissue hyperemia, edema, and nasal congestion commonly associated with colds or allergies. Other beneficial effects may include increasing the drainage of sinus secretions...
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Fluoroform is weakly acidic with a pK = 25–28 and quite inert. Attempted deprotonation results in defluorination to generate and difluorocarbene (). Some organocopper and organocadmium compounds have been developed as trifluoromethylation reagents. Fluoroform is a precursor of the Ruppert-Prakash reagent Trifluorometh...
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Greenhouse Gases
1,1-Difluoroethane, or DFE, is an organofluorine compound with the chemical formula CHF. This colorless gas is used as a refrigerant, where it is often listed as R-152a (refrigerant-152a) or HFC-152a (hydrofluorocarbon-152a). It is also used as a propellant for aerosol sprays and in gas duster products. As an alternati...
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Greenhouse Gases
Gestonorone caproate, also known as norhydroxyprogesterone caproate, 17α-hydroxy-19-norprogesterone 17α-hexanoate, or 17α-hydroxy-19-norpregn-4-ene-3,20-dione 17α-hexanoate, is a synthetic norpregnane steroid and a derivative of progesterone. It is specifically a combined derivative of 17α-hydroxyprogesterone and 19-no...
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Esomeprazole, sold under the brand name Nexium [or Neksium] among others, is a medication which reduces stomach acid. It is used to treat gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. Its effectiveness is similar to that of other proton pump inhibitors (PPIs). It is taken by mou...
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Carbon tetrachloride was discovered along with chloromethane and chloroform in oceans, marine algae and volcanoes. The natural emissions of carbon tetrachloride are too little compared to those from anthropogenic sources; for example, the Momotombo Volcano in Nicaragua emits carbon tetrachloride at a flux of 82 grams p...
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Acinetobacter anitratus, Acinetobacter calcoaceticus, Actinomyces odontolyticus, Aeromonas hydrophila, Bacteroides distasonis, Bacteroides uniformis, and Clostridium perfringens are generally susceptible to imipenem, while Acinetobacter baumannii, some Acinetobacter spp., Bacteroides fragilis, and Enterococcus faecali...
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Penicillamine is a trifunctional organic compound, consisting of a thiol, an amine, and a carboxylic acid. It is an amino acid structurally similar to cysteine, but with geminal dimethyl substituents α to the thiol. Like most amino acids, it is a colorless solid that exists in the zwitterionic form at physiological pH....
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